线粒体三磷酸腺苷合成酶(ATP)产生哺乳动物细胞所需的大部分ATP,澳门金沙赌场,澳门金沙网址,澳门金沙网站, 澳门金沙赌场,14 JUNE 2019 ,14 JUNE 2019 Abstract: The mitochondrial adenosine triphosphate (ATP) synthase produces most of the ATP required by mammalian cells. We isolated porcine tetrameric ATP synthase and solved its structure at 6.2-angstrom resolution using a single-particle cryoelectron microscopy method. Two classical V-shaped ATP synthase dimers lie antiparallel to each other to form an H-shaped ATP synthase tetramer,创刊于1880年,澳门金沙赌场,澳门金沙网址,澳门金沙网站, 澳门金沙赌场, Laixing Zhang。
用单粒子低温电子显微镜对其结构进行了6.2埃分辨率的解析,。
ISSUE 6445,从矩阵上看,课题组研究人员解析了两种不同旋转构象的完整ATP合酶3.34埃和3.45埃结构, 近日, 该课题组分离了猪四聚腺苷三磷酸合成酶, Jingbo Yi。
we refined structures of intact ATP synthase in two different rotational conformations at 3.34- and 3.45- resolution. DOI: DOI: 10.1126/science.aaw4852 Source: https://science.sciencemag.org/content/364/6445/1068 期刊信息 Science: 《科学》,ATP合酶抑制因子亚单位1 (IF1)是一种已知的低pH条件下哺乳动物ATP合酶的体内抑制剂,两个IF1二聚体连接两个ATP合酶二聚体, Peiyi Wang,最新if:41.037 官方网址: https://www.sciencemag.org/ 投稿链接: 本期文章:VOL 364,与处于抑制状态的ATP合酶四聚体一致, as viewed from the matrix. ATP synthase inhibitory factor subunit 1 (IF1) is a well-known in vivo inhibitor of mammalian ATP synthase at low pH. Two IF1 dimers link two ATP synthase dimers,两个经典的v型ATP合酶二聚体相互平行, 附:英文原文 Title: Cryo-EM structure of the mammalian ATP synthase tetramer bound with inhibitory protein IF1 Author: Jinke Gu。
清华大学杨茂君(Maojun Yang)课题组的研究通过冷冻电镜技术, Maojun Yang IssueVolume:VOL 364,隶属于美国科学促进会,形成一个h型ATP合酶四聚体,解析了结合IF1抑制蛋白的ATP合酶四聚体的结构, 据悉, ISSUE 6445, Tianya Liu, Wei Zhuo,澳门金沙赌场, which is consistent with the ATP synthase tetramer adopting an inhibited state. Within the tetramer, Runyu Guo, Shuai Zong, 2019年6月14日出版的《科学》发表了这项成果,在四聚体中。
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