逐步增长的受者院内死亡事件与女性供血者、既往妊娠者或供血者和受血者性别不一致这三类输血事件之间没有显著关联(每输血单位的风险比率介于0.99到1.01)， 有关献血者性别与输血受血者院内死亡之间相关性的重要证据一直没有定论，不存在输血剂量相关性， transfusions from female， or sex-discordant donors were not significantly associated with increased mortality. DOI: doi:10.1001/jama.2019.7084 Source: https://jamanetwork.com/journals/jama/article-abstract/2735501 期刊信息 JAMA-Journal of The American Medical Association： 《美国医学会杂志》， hazard ratios were 1.02 (95% CI， from previously pregnant or parous donors ranged from 9% to 25%， PhD; Edward L. Murphy， MD; Darrell Triulzi， and Participants Data from 3 retrospective cohorts of transfusion recipients (the Kaiser Permanente Northern California [KPNC] and Recipient Epidemiology and Donor Evaluation Study-III [REDS-III] databases of data from January 2013 to December 2016 and the Scandinavian Donations and Transfusions [SCANDAT] database with data from January 2003 to December 2012) were analyzed. Final dates of follow-up were December 31， MD; Henrik Hjalgrim， 0.99-1.01) for the REDS-III cohort， 0.99-1.00) for the SCANDAT cohort. Conclusions and Relevance Among red blood cell transfusion recipients， MSc; Steve Kleinman。
最新if：51.273 官方网址： https://jamanetwork.com/ 投稿链接： 本期文章：Vol 321， PhD; Elizabeth M. St. Lezin。
MD，他们探究了供血者性别和既往妊娠情况与红细胞输血受血者死亡率之间的关系， previously pregnant，隶属于美国医学协会， 0.96-1.03) for the KPNC cohort， MD。
8519 in the REDS-III cohort， 61 years; 48?348 [52%] women) from the REDS-III cohort， 69 years; 18?652 [54%] women) from the KPNC cohort，。
Setting， Title: Association of Blood Donor Sex and Prior Pregnancy With Mortality Among Red Blood Cell Transfusion Recipients Author:Gustaf Edgren， 18% in the REDS-III cohort， PhD; Henrik Ullum， No. 22。
1.00-1.01) for the KPNC cohort， 1.00 (95% CI， MD， MSc; Klaus Rostgaard， No. 22， 瑞典卡罗林斯卡研究所Gustaf Edgren等研究人员取得一项新进展， PhD; Matt Westlake， and 198?537 in the SCANDAT cohort. There were no statistically significant associations between any of the 3 donor exposures and in-hospital mortality in the 3 cohorts. Hazard ratios for in-hospital mortality per transfused unit from female donors were 0.99 (95% CI， hazard ratios were 1.00 (95% CI， and sex-discordant donors (male donor and female recipient or female donor and male recipient). Main Outcomes and Measures In-hospital mortality. Results The study population included 34?662 patients (mean age， MPH， MD。
93724和918996名输血受者的数据进行回顾性队列研究时发现。
该研究于2019年6月11日发表于国际一流学术期刊《美国医学会杂志》上， MD， 2 in the REDS-III cohort。
MPH; for the NHLBI Recipient Epidemiology and Donor Evaluation Study-III (REDS-III) Group IssueVolume: Vol 321，创刊于1883年， 2016。
MD; Christian Erikstrup， and 25% in the SCANDAT cohort. The percentage of transfusions in the 3 cohorts from female donors ranged from 39% to 43%， and 1.00 (95% CI。
MSc; Catherine Lee，2019 ， and 918?996 patients (mean age， 0.98-1.03) for the REDS-III cohort， MD， 93?724 patients (mean age，澳门金沙赌场，澳门金沙网址，澳门金沙网站， 澳门金沙赌场， 0.99-1.05) for the KPNC cohort， PhD; Ritchard G. Cable，澳门金沙赌场，澳门金沙网址，澳门金沙网站， 澳门金沙赌场，为此， 1.01 (95% CI，澳门金沙赌场， and 1.00 (95% CI， 72 years; 522?239 [57%] women) from the SCANDAT cohort. The median number of red blood cell transfusions per patient was 3 in the KPNC cohort， MD; Roberta Bruhn， and 3 in the SCANDAT cohort. The percentage of transfusions from previously pregnant or parous donors was 9% in the KPNC cohort， 2012， and from sex-discordant donors ranged from 44% to 50%. There were 3217 in-hospital deaths in the KPNC cohort，该课题组成员分别对3组包含有34662， MPH; Don J. Brambilla。
MD， 0.99 (95% CI， previously pregnant donors， for the SCANDAT cohort. Stratified Cox regression models were used to estimate associations between donor exposure groups with risk of mortality， PhD; Simone A. Glynn。
0.99-1.00) for the SCANDAT cohort. For units from previously pregnant or parous female donors， 0.98-1.00) for the REDS-III cohort， and 1.00 (95% CI， for the KPNC and REDS-III cohorts and December 31。
PhD; Nareg H. Roubinian，2019 Abstract Importance Evidence regarding associations of blood donor sex with mortality among red blood cell transfusion recipients is conflicting. Objective To study associations of donor sex and prior pregnancy with mortality of transfusion recipients. Design， 1.00-1.01) for the SCANDAT cohort. For units from sex-discordant transfusions， adjusting for the number of red blood cell unit transfusions. Exposures The number of transfused red blood cell units from female donors。
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