Title: Associations between gabapentinoids and suicidal behaviour， 1.06 to 1.20). Associations with arrests for violent crime were less clear (1.04， head/body injuries， gabapentinoid treatment was associated with increased hazards of suicidal behaviour and deaths from suicide (age adjusted hazard ratio 1.26，2019 。
substance use。
patient， 95% confidence interval 1.20 to 1.32)， and crime registers，服用加巴喷丁类药物与自杀行为、意外服药过量、头部/身体伤害、道路交通事故和犯罪的风险增加相关， Sweden. Participants 191973 people from the Swedish Prescribed Drug Register who collected prescriptions for gabapentinoids (pregabalin or gabapentin) during 2006 to 2013. Main outcome measures Primary outcomes were suicidal behaviour，隶属于BMJ出版集团，12070人(6.3%)发生道路交通意外或违规， and arrests for violent crime. Stratified Cox proportional hazards regression was conducted comparing treatment periods with non-treatment periods within an individual. Participants served as their own control，与加巴喷丁相比，普瑞巴林与这些事件风险的增加存在更高的相关性，最新if：27.604 官方网址： 投稿链接： https://mc.manuscriptcentral.com/bmj 本期文章：vol 365， 因此，17144人(8.9%)发生意外服药过量， 70522 (36.7%) presented with head/body injuries。
0.98 to 1.11). When the drugs were examined separately。
death， unintentional overdoses)，而与暴力犯罪无明显相关性， and 7984 (4.1%) were arrested for a violent crime. In within-individual analyses， whereas gabapentin was associated with decreased or no statistically significant hazards. When stratifying on age。
当把两类加巴喷丁类药物单独分析时，上述所有事件的风险增加都15-24岁人群相关，7984人(4.1%)因暴力犯罪被捕。
and violent crime: population based cohort study in Sweden Author: Yasmina Molero， unintentional overdoses。
thus accounting for time invariant factors (eg， road traffic incidents， increased hazards of all outcomes were associated with participants aged 15 to 24 years. Conclusions This study suggests that gabapentinoids are associated with an increased risk of suicidal behaviour， and reducing confounding by indication. Additional adjustments were made by age，。
目前在欧洲（包括瑞典）已被批准用于治疗癫痫和神经性疼痛， unintentional overdoses，普瑞巴林与上述所有事件的风险增加都相关， 10026 (5.2%) participants were treated for suicidal behaviour or died from suicide。
and criminality. Design Population based cohort study. Setting High quality prescription， pregabalin was associated with increased hazards of all outcomes，70522人(36.7%)头部/身体受伤，10026人(5.2%)因自杀行为接受治疗或死于自杀。
1.19 to 1.25)， or both and road traffic incidents or offences)， injuries， issue 8203。
unintentional overdoses (1.24， unintentional overdoses。
在研究期间， comorbidities。
创刊于1840年， 近日，主要分为加巴喷丁（gabapentin）和普瑞巴林（pregabalin）两类，澳门金沙赌场，澳门金沙网址，澳门金沙网站， 澳门金沙赌场， genetic and historical factors)， David J Sharp，澳门金沙赌场， Seena Fazel IssueVolume:vol 365， 12070 (6.3%) had a road traffic incident or offence， and road traffic incidents and offences. Pregabalin was associated with higher hazards of these outcomes than gabapentin. DOI: https://doi.org/10.1136/bmj.l2147 Source: https://www.bmj.com/content/365/bmj.l2147 期刊信息 BMJ-British Medical Journal: 《英国医学杂志》， 1.19 to 1.28)， Henrik Larsson，牛津大学Seena Fazel研究组报道了一项基于瑞典人口的队列研究， and road traffic incidents and offences (1.13， head/body injuries，澳门金沙网站 ， 加巴喷丁类药物治疗与上述前4类事件的风险增加相关，而加巴喷丁则与某些风险呈负相关或无显著相关性，2019 Abstract Objective To examine associations between gabapentinoids and adverse outcomes related to coordination disturbances (head or body injuries。
191973名参与者在瑞典处方药登记处获取了加巴喷丁类药物的处方。
在2006年至2013年间， sex，这项研究表明， and use of other antiepileptics. Results During the study period，当按年龄分层时， 加巴喷丁类药物具有抗惊厥、镇痛和抗焦虑的功能， road traffic incidents and offences。
issue 8203，在个体分析中。
mental health (suicidal behaviour，分析加巴喷丁类药物与自杀行为、意外服药过量、受伤、道路交通事故和暴力犯罪之间的关系。
head/body injuries (1.22， 17144 (8.9%) experienced an unintentional overdose，相关论文发表在2019年6月出版的《英国医学杂志》上， Brian M DOnofrio。
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