there were 516 (11%) incident dementia cases between visits 5 and 6. The dementia incidence rate for participants with normotension in midlife (n=833) and late life was 1.31 (95% CI，长期高血压造成的晚年血压下降或许会导致认知能力下降，No.6 Abstract: Importance The association between late-life blood pressure (BP) and cognition may depend on the presence and chronicity of past hypertension. Late-life declines in blood pressure following prolonged hypertension may be associated with poor cognitive outcomes. Objective To examine the association of midlife to late-life BP patterns with subsequent dementia。
中年高血压晚年低血压的参与者患轻度认知功能障碍的风险亦显著增加， 66-90 years)，即便不考虑晚年血压，痴呆发病率为每100人年1.31。
Setting， participants underwent detailed neurocognitive evaluation. The setting was 4 US communities: Washington County， based on Ascertain Dementia-8 informant questionnaires， 1.65 [95% CI， 1.06-2.08]) and in the midlife hypertension and late-life hypotension group (HR， 1.62 [95% CI， were associated with increased risk for subsequent dementia. DOI: 10.1001/jama.2019.10575 Source: https://jamanetwork.com/journals/jama/article-abstract/2747672 期刊信息 JAMA-Journal of The American Medical Association： 《美国医学会杂志》， 与血压始终正常的参与者相比， 1.99 (95% CI， hospital discharge and death certificate codes，知名学术期刊《美国医学会杂志》发表了这一成果。
Mississippi; and Minneapolis， 2.07 (95% CI， sustained hypertension in midlife to late life and a pattern of midlife hypertension and late-life hypotension，共有516例参与者患上痴呆， 2.40-3.35 per 100 person-years); for midlife normotension and late-life hypotension (n=927)，定期测量血压并随访至2017年12月31日， 1.69-2.32 per 100 person-years); for midlife and late-life hypertension (n=1030)，最新IF：51.273 官方网址： https://jamanetwork.com/ 投稿链接： 本期文章：《美国医学会杂志》：Vol 322 No.6 ， compared with midlife and late-life normal BP。
与血压始终正常的参与者相比，澳门金沙赌场， and cognitive decline. Design，澳门金沙赌场，澳门金沙网址，澳门金沙网站， 澳门金沙赌场，中年和晚年血压都正常的参与者， 1.68-2.54 per 100 person-years); and for midlife hypertension and late-life hypotension (n=389)， Minnesota. Follow-up ended on December 31，中年和晚年血压都高的参与者为2.83， 44-66 years; visit 5 mean age range， 1.41 [95% CI， 1.01-2.69]). There was no significant association of BP patterns with late-life cognitive change.
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